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The results of phase 2 (dose-ranging) trials with primary endpoints of HbA 1c change (Rosenstock et al, 2023) and body-weight change (Jastreboff et al, 2023) are shown in Table 6
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Another compound, wogonin, has been reported to inhibit the Nrf2/GPX4 axis, leading to the accumulation of lipid peroxides and iron, thereby inducing ferroptosis in PDAC [152]
Schuettpelz et al., 2014
No disease or therapeutic claims are made or implied
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